I take the 25/100 dose, 4 t/p/y. Last dose I take is about 8or 9. Then none until 5 a.m. if your pain is at night try adjusting your time schedule.

No I'm taking c/l 25-100 11/2 4 times a day I'll talk to my dr

Have you tried the C/L extended release? I have no down time since taking it. Just don’t skip a dose. I take 2 every 5 hours— 5 a.m., 10. 3, 8. Right now that’s working but as you know— things change.

I had an off time the other morning I wasn't sure what the problem was I just didn't feel like doing anything and that's not me but I read off time is usually when meds wear off