I was on SinemetC-R. The pharmicit gave me plain Sinemet by mistake. I liked it better. I found the absorption of the Sinermet C-r to be irrati
and led to on-off reations THt was just my experence.

I have been on both and went back on the single dose because I didn't feel the improvement very fast . Now my neurologist has taken me off both so will see what happens

My husband has been in a morning and evening CR for years--

my husband tried that one when he was first diagnosed. it made him fall asleep on the way home from work!! Not good. So he just now takes the regular carb/dopa