I was on SinemetC-R. The pharmicit gave me plain Sinemet by mistake. I liked it better. I found the absorption of the Sinermet C-r to be irrati
and led to on-off reations THt was just my experence.

The nickname for sinemet CR is "crappy release" because it is inconsistent. But the plus side is you are not popping pills all day!

I have been on both and went back on the single dose because I didn't feel the improvement very fast . Now my neurologist has taken me off both so will see what happens

My husband has been in a morning and evening CR for years--

my husband tried that one when he was first diagnosed. it made him fall asleep on the way home from work!! Not good. So he just now takes the regular carb/dopa