My paternal grandfather had PD.
I was tested for gene mutations that give a greater risk of getting Parkinson's and I don't have them.
.Most cases of Parkinson disease occur in people with no apparent family history of the disorder. These sporadic cases may not be inherited, or they may have an inheritance pattern that is unknown.
Among familial cases of Parkinson disease, the inheritance pattern differs depending on the gene that is altered. If the LRRK2 or SNCA gene is involved, the disorder is inherited in an autosomal dominant pattern, which means one copy of an altered gene in each cell is sufficient to cause the disorder. In most cases, an affected person has one parent with the condition.
If the PARK2, PARK7, or PINK1 gene is involved, Parkinson disease is inherited in an autosomal recessive pattern. This type of inheritance means that two copies of the gene in each cell are altered. Most often, the parents of an individual with autosomal recessive Parkinson disease each carry one copy of the altered gene but do not show signs and symptoms of the disorder.
My fiancé had his father with PD; father's sister had two boys one w MS and the other w PD. He also had
a grandmother w PD......can you say inherited. Alz, MS, PD, ALS are all Neurodegenerative Disorders and closely related.
My Dad had PD. He had tremors from very young, but it never apparrently really progressed, like me. He was on medication for PD, but it was never mentioned and I only found out when he was hospitalised following a fall. When I was diagnosed, I made sense of some of my poor Dad's disabilities. It was initially assumed I may have the PD associated with Fragile X syndrome; of which both My Father and I are carriers. This was shown not to be so.
My maternal grandfather had PD. It's mentioned on his death certificate.