I, too, take carbidopa-levadopa --1 tablet 4 times a day. I was a mess before I was diagnosed -- I could not button my coat, write a neat sentence in script, buckle my seat belt; my hands shook so I could not pull up or button my trousers, and so on. Carbidopa-levadopa and a terrific neurologist changed all that; it felt as if I'd taken a miracle drug. Except for brief down times between doses, the pills have worked amazingly these past two years, returning my life to what it was like before PD.

My wife has taken it for at least 20 years. She uses 3.0 er now just once a day. a necessary drug for her

At first the carbidopa levodopa seemed to help mom. Now her non motor symptoms seem to increase rapidly but it still helps with the motor symptoms.

I was on carbidopa levadopa at first it work decent for about 6 months than I was back almost like I was before being on med neurologist started me on rytary and the difference was significantly better I also take requip with the rytary also seems like the rytary last longer and so far don't have as many bad days like I was before and not lag time between doses also take a muscle relaxer for my dystonia seems to help a lot also especially at night another thing I don't have near the not being able to sit still with the new Med

She takes carbidopa-levodopa, Neupro patch, and Nuplazid.