My HWP takes Sertraline and Amitriptyline for depression. This have helped him a lot. I don’t have PD but take Lexapro for my anxiety and depression, and it helps so much. My HWP was on Lexapro which his doc says is good and okay for people with PD, but they switched him to the other meds because he wasn’t experiencing anxiety and they thought those would be better for his depression. They have helped him a lot.