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About DBS -postop Outcomes And Advise
A MyParkinsonsTeam Member asked a question đź’­

Hi All, if you have had DBS could you let us know of the process before the op and the post-operative outcomes.

posted November 10, 2023
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A MyParkinsonsTeam Member

Thank you Maria, very informative. 🍎

posted November 10, 2023
A MyParkinsonsTeam Member

Below is a portion of an update on the current state of DBS. It was published by NIH on the PubMedCentral site. You can search for the entire article on the PMC site under #PMC (Phone number can only be seen by the question and answer creators)
Deep Brain Stimulation (DBS)
For those whose motor symptoms are debilitating and cannot be controlled with medications, or whose side effects from medications are severe, deep brain stimulation (DBS) may be an option. You and your doctor should decide together whether DBS may be right for you.

DBS involves the implantation of a three-part device to block electrical signals that cause tremors and other motor symptoms of Parkinson’s. Data from over 1000 patients with PD and STN-DBS showed improvements in motor symptoms (50%) and activities of daily living (52%) according to the Unified Parkinson’s Disease Rating Scale (UPDRS) [92,93]. Specifically for tremor, improvements between 70–75% at one year following surgery were reported, and these improvements remained stable at five years [91].

STN-DBS is generally favored over GPi stimulation for treatment of tremor, tremor responds similarly to both, and both targets show equal improvements in motor functioning. STN-DBS allows more reduction in antiparkinsonian medication [97,100,101]. However, bilateral GPi-DBS has been proven to significantly reduce tremor with 32–80% after 1 year [102,103,104] and 70% after 5–6 years [105]. Additionally, unilateral GPi-DBS showed tremor reduction between 47–71% [103,106].

Nowadays, STN and GPi represent the preferred targets for tremor control in PD because of their effect on rigidity and bradykinesia. The choice between the two is based on individual consideration (e.g., pharmacological management, non-motor-symptoms), although evidence suggested a slight superiority of STN-DBS over GPi-DBS (Figure 1) [87].d in two different surgeries. The first surgery is usually performed while you are awake, with a local anesthetic to numb your scalp. The first surgery will take three to six hours. You can expect to stay in the hospital for two to three days after this surgery. The second surgery will happen about a week later. You will be under general anesthetic for this surgery, which will involve placing a pulse generator device containing batteries on your chest wall. You will likely spend less than 24 hours in the hospital after the second surgery. It may take as long as six months of adjusting your DBS settings before you experience benefits from the surgery.

DBS surgery may not be successful in controlling your motor symptoms. Any surgery carries risks including blood clots, blood loss, infection, breathing problems, reactions to medication, and heart attack or stroke during the surgery. Rarely, DBS surgery can cause seizures.
Hope this is helpful and informative.
Maria

posted November 10, 2023
A MyParkinsonsTeam Member

What is DBS?

posted November 10, 2023
A MyParkinsonsTeam Member

Robyn, Below is a portion of an article posted in the My Parkinson's team website. Please check out the entire article in the resource folder on that site. Also, Cleveland Clinic has a description of the DBS process on their site. You may want to check these out for more detail but Some folks in our community may have experienced DBS and be willing to share their experience.

Brain Stimulation (DBS)
For those whose motor symptoms are debilitating and cannot be controlled with medications, or whose side effects from medications are severe, deep brain stimulation (DBS) may be an option. Your neurologist will perform extensive testing to find out whether you are a good candidate for DBS. You and your doctor should decide together whether DBS may be right for you.

DBS involves the implantation of a three-part device to block electrical signals that cause tremors and other motor symptoms of Parkinson’s. DBS is implanted in two different surgeries. The first surgery is usually performed while you are awake, with a local anesthetic to numb your scalp. The first surgery will take three to six hours. You can expect to stay in the hospital for two to three days after this surgery. The second surgery will happen about a week later. You will be under general anesthetic for this surgery, which will involve placing a pulse generator device containing batteries on your chest wall. You will likely spend less than 24 hours in the hospital after the second surgery. It may take as long as six months of adjusting your DBS settings before you experience benefits from the surgery.

DBS surgery may not be successful in controlling your motor symptoms. Any surgery carries risks including blood clots, blood loss, infection, breathing problems, reactions to medication, and heart attack or stroke during the surgery. Rarely, DBS surgery can cause seizures.

posted November 10, 2023

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