Have you talked to your doctor about Duopa, it's Carbo/Levodopa in a suspension form that comes in cartridges and they are then hooked to a pump, which feeds you medicine throughout the day. It does require having a jpeg tube placed in your abdomen but that is a small price to pay if it works for you like it has for me. ABBVIE has a website on it called DUOPA.COM
Check it out. If you think it might be right for you, contact me on here and I will share my experience with Duopa. I've had it since October 2022. I don't know what your symptoms are, but I was on 24 pills a day and was only getting 10 "on time" from each dose. My off periods were alot more prevaalent than my "on period". It has made life so much better. I pray this helps you. They also have mentors that you can call and talk to, that should be able to answer you questions. But, again, I am happy to share my story with you. Just contact me🙏💕

Thank you Anita. It's my husband, Ed who has PD. I’m his wife and caregiver.

CherylJollie I am sorry that you are having a hard time. You will be in my prayers. Hugs and I pray they find something that works for you.🙏🫂🙏

Thank you. Yes, have been on Duopa for 18 months. Duopa was not working as well as it did initially, so tried the Vyalev. Vyalev didn’t work, so back on Duopa. Problem is, many days dyskinesia starts up early in the day, so have to stop the Duopa, then off time sets in. Can usually restart the Duopa and extend day a little longer. Have tried reducing continuous rate to prevent too much build up, sometimes this works and sometimes it doesn’t. Every day is it’s on day and not one day is the same. I’m living a life of predictable unpredictability. There is Apokyn, Doctor recommend, although many side effects associated with the medication. One day at a time is what’s left. Hoping for a miracle and cure for this dreadful disease.