Ask your doctor. My husband was recently tested for both B6 and B12 after I read the article about the risk of B6 deficiency. His B6 was normal but his B12 was a bit low so he is supplementing that now.
June 3
The question of how much vitamin B6 to supplement is an important one, especially if taking carbidopa/levodopa for Parkinson's.
The FDA has flagged that carbidopa/levodopa can lower B6 levels over time, particularly at higher doses (above 1,000 mg/day). Because of this, doctors are now advised to check B6 levels before and Show Full Answer
The question of how much vitamin B6 to supplement is an important one, especially if taking carbidopa/levodopa for Parkinson's.
The FDA has flagged that carbidopa/levodopa can lower B6 levels over time, particularly at higher doses (above 1,000 mg/day). Because of this, doctors are now advised to check B6 levels before and during treatment.
There is no one-size-fits-all dosage recommendation for B6 supplementation — the right amount depends on your current levels, which can only be determined through a blood test.
Here's what to keep in mind:
- Get tested first — ask your doctor to check your B6 levels before starting any supplement
- Don't self-dose — too much B6 can also cause nerve-related symptoms, so more isn't always better
- Watch for warning signs — numbness, tingling, mood changes, or fatigue could signal low B6
- Never adjust your carbidopa/levodopa dose on your own — always consult your doctor first
The safest step is to bring this up at your next appointment and ask whether B6 testing or supplementation is right for your specific situation.
June 3
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