Does the combination of drugs help with ridigity?
June 15
It sounds like you're asking about Amantadine (not Amandine — easy mix-up!) as an add-on medication alongside carbidopa/levodopa. Great question!
Amantadine is indeed used alongside carbidopa/levodopa and is FDA-approved specifically to help manage levodopa-induced dyskinesia (those involuntary, uncontrolled movements that Show Full Answer
It sounds like you're asking about Amantadine (not Amandine — easy mix-up!) as an add-on medication alongside carbidopa/levodopa. Great question!
Amantadine is indeed used alongside carbidopa/levodopa and is FDA-approved specifically to help manage levodopa-induced dyskinesia (those involuntary, uncontrolled movements that can develop after long-term levodopa use).
It comes in a few formulations:
- Gocovri (extended-release)
- Osmolex ER (extended-release)
It's believed to work by boosting dopamine availability in the brain and helping to calm overactive muscle movement signals. Members of MyParkinsonsTeam have shared positive experiences with dosage adjustments alongside amantadine. One member noted that when their doctor lowered their Sinemet dose, dyskinesia disappeared — showing that a combined approach can really make a difference.
As with any medication, there are things to watch for. Always check with your neurologist before adding or adjusting anything, as everyone's response can be different.
June 15
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