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About MyParkinsonsTeam

Mirapex is a prescription drug approved by the Food and Drug Administration (FDA) in 1997 to treat motor symptoms of Parkinson’s Disease. Mirapex is also referred to by its drug name, pramipexole.

Mirapex is not suitable for use in people with a major psychotic disorder or those who have previously shown hypersensitivity to pramipexole. Mirapex must be used with caution in people with high or low blood pressure, asthma, schizophrenia, sleep disorders, heart problems, kidney problems, or a history of alcohol addiction. Mirapex may not be appropriate for women who are pregnant or breastfeeding.

Mirapex is a member of a class of drugs called dopamine agonists. Mirapex is believed to work by imitating the action of dopamine in the brain.

Some medications are available both as generic and branded products. Although generic and branded formulations of a drug contain the same active ingredients at the same concentrations, your body may react differently to different formulations. Check with your doctor before switching between drug brands or between generic and branded drugs.

How do I take it?
Mirapex is taken orally as a tablet three times a day. Mirapex may be taken with or without food. Taking Mirapex with food may help prevent stomach upset. Take Mirapex at the same times each day.

Do not drink alcohol while you are taking Mirapex. Alcohol can increase the intensity of some side effects.

Avoid driving or operating machinery while using Mirapex.

Do not stop using Mirapex suddenly. If you decide to stop using Mirapex, form a plan with your doctor for gradually tapering off your dosage to avoid withdrawal symptoms.

Always follow your doctor’s instructions exactly when taking Mirapex.

The results of a study published in 2005 indicated that pramipexole (Mirapex) is effective and tolerable for the long-term treatment of Parkinson’s Disease. The study involved 354 people with Parkinson’s Disease, some of whom took the drug for as long as 57 months.

Side effects
Common side effects of Mirapex include nausea, vomiting, stomach upset, constipation, low blood pressure, dizziness upon standing, fainting, memory problems, drowsiness, loss of appetite, vision or weight changes, sleep problems, sexual dysfunction, difficulty or pain during urination, increased frequency of urination, fluid retention, dry mouth, joint pain, and swelling of the extremities. Tell your doctor if these side effects become worse.

Inform your doctor immediately if you experience a fast, pounding, or uneven heartbeat, rigid muscles, muscle cramps, fever, chest pain, agitation, hallucinations, impulsive or psychotic behavior, slurred speech, or seizures while taking Mirapex.

Rarely, dopamine agonists such as Mirapex may contribute to the development of serious lung or heart valve problems including pleural effusion, retroperitoneal fibrosis, or cardiac valvulopathy. These conditions may or may not resolve after you stop taking the drug.

Many drugs can cause allergic reactions that in the most serious cases, can result in death. Seek immediate medical help if you experience signs of a severe allergic reaction such as hives, difficulty breathing, or swelling in the face, throat, eyes, lips, or tongue.

Mirapex (Pramipexole) for Parkinson's disease Questions

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