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About MyParkinsonsTeam

Mirapex ER is a prescription drug approved by the Food and Drug Administration (FDA) in 2010 to treat motor symptoms of Parkinson’s Disease. Mirapex ER is also referred to by its drug name, pramipexole.

Mirapex ER is not suitable for use in people with a major psychotic disorder or those who have previously shown hypersensitivity to pramipexole. Mirapex ER must be used with caution in people with high or low blood pressure, asthma, schizophrenia, sleep disorders, heart problems, kidney disease, or a history of alcohol addiction. Mirapex ER may not be appropriate for women who are pregnant or breastfeeding.

Mirapex ER is a member of a class of drugs called dopamine agonists. Mirapex ER is believed to work by imitating the action of dopamine in the brain.

Some medications are available both as generic and branded products. Although generic and branded formulations of a drug contain the same active ingredients at the same concentrations, your body may react differently to different formulations. Check with your doctor before switching between drug brands or between generic and branded drugs.

How do I take it?
Mirapex ER is taken orally as a tablet once a day. Mirapex ER may be taken with or without food. Taking Mirapex ER with food may help prevent stomach upset. Take Mirapex ER at the same time each day. Do not crush, chew, or split Mirapex ER tablets.

Do not drink alcohol while you are taking Mirapex ER. Alcohol can increase the intensity of some side effects.

Avoid driving or operating machinery while using Mirapex ER.

Do not stop using Mirapex ER suddenly. If you decide to stop using Mirapex ER, form a plan with your doctor for gradually tapering off your dosage to avoid withdrawal symptoms.

Always follow your doctor’s instructions exactly when taking Mirapex ER.

The results of a study published in 2005 indicated that pramipexole (Mirapex ER) is effective and tolerable for the long-term treatment of Parkinson’s Disease. The study involved 354 people with Parkinson’s Disease, some of whom took the drug for as long as 57 months.

Side effects
Common side effects of Mirapex ER include nausea, vomiting, stomach upset, constipation, low blood pressure, dizziness upon standing, fainting, memory problems, drowsiness, loss of appetite, vision or weight changes, sleep problems, sexual dysfunction, difficulty or pain during urination, increased frequency of urination, fluid retention, dry mouth, joint pain, and swelling of the extremities. Tell your doctor if these side effects become worse.

Inform your doctor immediately if you experience a fast, pounding, or uneven heartbeat, rigid muscles, muscle cramps, fever, chest pain, agitation, hallucinations, impulsive or psychotic behavior, slurred speech, or seizures while taking Mirapex ER.

Rarely, dopamine agonists such as Mirapex ER may contribute to the development of serious lung or heart valve problems including pleural effusion, retroperitoneal fibrosis, or cardiac valvulopathy. These conditions may or may not resolve after you stop taking the drug.

Many drugs can cause allergic reactions that in the most serious cases, can result in death. Seek immediate medical help if you experience signs of a severe allergic reaction such as hives, difficulty breathing, or swelling in the face, throat, eyes, lips, or tongue.

Mirapex ER (Pramipexole) for Parkinson's disease Questions

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