Maybe it's just because you're excited or a little bit nervous. I've noticed that anytime I'm not calm and peaceful I seem to have more symptoms .

Again, it's all that sitting. On the plane, waiting here and there, rental car sitting, think how your movement changes when you notice your meds aren't as effective. Try journaling in a small notebook you keep in your pocket. Might find clues that only you can uncover. Your MD can't know what you do, only you can.

I've noticed that a little bit when I traveled earlier this year. I also find that if I exercise or exert myself physically that my meds wear off faster. Stress of traveling or activity seems to cause a quicker use of the medication dosages.

I tbouht it was just me. Good to know I'm not alone. Airport and pre-trip planning and getting on plane produce symptoms right away.

My meds wear off the instant I get upset or expel any extra energy.. I am glad it’s not just me.