Supposedly coming out in 2017 is something new for the "on-off" symptoms we experience with PD. Has anyone heard of it? Research is being done by Dr. Robert Hauser of the University of South Florida. The new treatment could provide relief to people who wake up experiencing slowness and stiffness, Anyone interested there is a clinical trial in Tampa at the USF Health Byrd Parkinsons Disease and Movement Disorders Center. Thought… read more
@A MyParkinsonsTeam Member. Hey Alan...thanks for the heads up research. There was another member today who tells us about an unfreezing drug that dissolves under the tongue. Help me look for it. It is not called Zelapar though. I can't remember the name but will recognize it if I see it. It was posted today I believe. Sterling
Hi @ Sterling... I was unfamiliar with Zelapar too, so I went to the Valeant Pharmaceutical the Mfg.
Here is what they say..... Basically it's essentially doing the same thing Comtan (entacapone - generic name) which "extends" the utilization of the levodopa/carbidopa (Sinemet), except this one dissolves under your tongue, and by itself does nothing without Sinemet. Alan
ZELAPAR (selegiline hydrochloride) is indicated as an adjunct therapy for Parkinson's disease patients being treated with levodopa/carbidopa who exhibit deterioration in the quality of their response to this therapy. There is no evidence from controlled studies that ZELAPAR has any beneficial effect in the absence of concurrent levodopa therapy.
My Parkinson's physician prescribed "an emergency" form of Carbidopa-Levo (25-100 mg) to be taken when I freeze-up and am unable to walk. This form of Carbidopa-Levo (Parcopa 25-100 mg ODT) is placed under the tongue and allowed to dissolve. This allows the Dopamine to reach the blood-stream and brain much faster than Carbidopa-Levo in its usual form. For me, Parcopa ODT reaches in the brain and begins to unfreeze me in 15 min as compared to1.5 hr for the normal form of Carbidopa-Levo. Parcopa ODT is manufactured by MYLAN, Parcopa ODTdoes not replace normal form of Carbidopa-Levo; it supplements it.
I have heard of it and applied for a study but was not accepted because I have asthma.