@A MyParkinsonsTeam Member. Hey Alan...thanks for the heads up research. There was another member today who tells us about an unfreezing drug that dissolves under the tongue. Help me look for it. It is not called Zelapar though. I can't remember the name but will recognize it if I see it. It was posted today I believe. Sterling

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A MyParki...

Hi @ Sterling... I was unfamiliar with Zelapar too, so I went to the Valeant Pharmaceutical the Mfg.

Here is what they say..... Basically it's essentially doing the same thing Comtan (entacapone - generic name) which "extends" the utilization of the levodopa/carbidopa (Sinemet), except this one dissolves under your tongue, and by itself does nothing without Sinemet. Alan

ZELAPAR (selegiline hydrochloride) is indicated as an adjunct therapy for Parkinson's disease patients being treated with levodopa/carbidopa who exhibit deterioration in the quality of their response to this therapy. There is no evidence from controlled studies that ZELAPAR has any beneficial effect in the absence of concurrent levodopa therapy.

My Parkinson's physician prescribed "an emergency" form of Carbidopa-Levo (25-100 mg) to be taken when I freeze-up and am unable to walk. This form of Carbidopa-Levo (Parcopa 25-100 mg ODT) is placed under the tongue and allowed to dissolve. This allows the Dopamine to reach the blood-stream and brain much faster than Carbidopa-Levo in its usual form. For me, Parcopa ODT reaches in the brain and begins to unfreeze me in 15 min as compared to1.5 hr for the normal form of Carbidopa-Levo. Parcopa ODT is manufactured by MYLAN, Parcopa ODTdoes not replace normal form of Carbidopa-Levo; it supplements it.

@A MyParkinsonsTeam Member. You were just added to my team...Team Sterling. Welcome...we are more than happy you have joined us. You are now in the company of your huge Parkinson's family.

Your subject matter is most interesting to me. I wonder how many PDers know about this method of getting free from freezing. I have a feeling most do not know about it. It's called Parcopa ODT and is manufactured by MYLAN. You tell us that Parcopa ODTdoes not replace the normal form of Carbidopa-Levo but it supplements it. Plus there is less waiting time for it to be effective. I think this is awesome.

Any side effects from Parcopa ODT for you? Thank you for posting us. Best and warmest wishes to you FCP. Sterling

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A MyParki...

I have heard of it and applied for a study but was not accepted because I have asthma.