I only take sinemet, but yes, sometimes when it’s wearing off and now and then when it’s supposed to be working.

I have 'off' days all the time 😏 sometimes it's my seizures acting up, not actually having one, just skimming below the threshold. Now I know I can add Parkinson's to the list 🙄 oh well, I guess ill call them yuk days. I'm in recovery mode today as yesterday was dedicated to my IBD. From 3PM till 11pm, I was on the floor, the throne or in the tub (seizure protective devise) the whole time. It is worse than Epilepsy or Parkinson's together 😡 My poor husband just sits in helplessness. I hate it. But it's over now 😊 time to heal for a day or two. I hope you have more good days than off days 😁

I have shortness of breath any time I go walking or vacuuming or any slightly strenuous activity. You only have when your meds are wearing off? All meds or specific ones?