My husband who doesn’t have PD was put on a low dose of Gabapentin for another reason and within one week had a major change to his personality experiencing bouts of anxiety, extreme sadness and sometimes anger. As soon as he stopped taking it he returned to his own level personality. I agree that research is vital and being your own best advocate.
🌈TheaD

We all experience it especially us who have had it awhile

I've read that anywhere from 30-70% of PD patients experience cognitive decline. It can be minor (losing words) to major (dementia or psychosis). I don't know if gabapentin makes it worse. Carbidopa doesn't seem to affect it, unfortunately. Losing executive function seems to be really common, even in the fairly early stages.

I am still using the Gabapentin. It's really hard to know whether or not that's the reason for my cognitive decline. I do know that it helps with the dystonia. I've begun to figure out that it's all a compromise. You have to choose which symptoms and side effects you can live with and those you can't. It depends on the day, frankly. My nurse practitioner is so good, very patient, we keep trying for the right cocktail, and if the cocktail needs to be adjusted, then we adjust it. It's the nature of the Beast, right? Thank you for being so helpful.

I swear that my husband didn’t have any problems til he took Gabipentin for TMJ issues. (Given by a dentist ) Hard to say if it’s the main problem but I made him stop it and he’s been much better and hasn’t had as much trouble speaking or finding words.🤷🏻‍♀️