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Real members of MyParkinsonsTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyParkinsonsTeam Member asked a question 💭
Aberdeen, NC
November 11, 2025
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A MyParkinsonsTeam Member

Anne what do you take 6 times a day please?

November 11, 2025
MyParkinsonsTeam

Yes, many people with Parkinson's experience challenging "off" times when medication effectiveness decreases. These periods can significantly impact daily life and vary widely between individuals.

MyParkinsonsTeam members report various symptoms during "off" times:

* Severe gait problems and dragging legs
* Return of Show Full Answer

Yes, many people with Parkinson's experience challenging "off" times when medication effectiveness decreases. These periods can significantly impact daily life and vary widely between individuals.

MyParkinsonsTeam members report various symptoms during "off" times:

* Severe gait problems and dragging legs
* Return of tremors and muscle stiffness
* Extreme fatigue and shortness of breath
* Difficulty moving at all
* Balance issues
* Muscle pain
* Toe curling
* Facial squinting or tics
* Difficulty talking
* Urinary incontinence

One member described their experience: "My gait gets really bad, hand tremor returns, and tics in my legs keep me from sleeping." Another shared, "The medicine wears off and I can't move."

The good news is that "off" time can be managed. Some members have found relief through medication adjustments, while others celebrate days without "off" periods as particularly good days. Working with your doctor to optimize your medication schedule and exploring different management strategies can help minimize these difficult periods.

You're not alone in this experience - it's a common challenge that many in the Parkinson's community navigate together.

November 11, 2025

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