How has Nuplazid been working for managing your wife's hallucinations?
Nuplazid (pimavanserin) was the first antipsychotic approved by the FDA specifically for Parkinson's psychosis. What makes it different from older antipsychotics is that it doesn't worsen motor symptoms, which was a major problem with previous Show Full Answer
How has Nuplazid been working for managing your wife's hallucinations?
Nuplazid (pimavanserin) was the first antipsychotic approved by the FDA specifically for Parkinson's psychosis. What makes it different from older antipsychotics is that it doesn't worsen motor symptoms, which was a major problem with previous medications.
The drug works by influencing serotonin rather than dopamine, which is why it can help with hallucinations without affecting movement. This was a significant breakthrough since people previously had to choose between managing hallucinations or preserving motor function. It's important to be aware of potential side effects. Common ones include:
- Confused state
- Peripheral edema (swelling of legs, feet, or ankles)
There are also rare but serious risks, including an increased risk of death in older adults with dementia. The FDA has been monitoring safety reports for this medication.
If you're experiencing any concerning side effects or if the medication isn't working as hoped, talk with your wife's neurologist about adjusting the treatment plan. They can help weigh the benefits versus risks for her specific situation.
January 14
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