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A MyParkinsonsTeam Member asked a question 💭
Hilton Head Isle, SC
April 21
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Can antidepressant medication cause Parkinson's disease?

Certain antidepressants, specifically SSRIs (selective serotonin reuptake inhibitor antidepressants) like fluoxetine (Prozac) and sertraline (Zoloft), can cause drug-induced parkinsonism, but this is different from Parkinson's disease itself.

Drug-induced Show Full Answer

Can antidepressant medication cause Parkinson's disease?

Certain antidepressants, specifically SSRIs (selective serotonin reuptake inhibitor antidepressants) like fluoxetine (Prozac) and sertraline (Zoloft), can cause drug-induced parkinsonism, but this is different from Parkinson's disease itself.

Drug-induced parkinsonism creates symptoms that mimic Parkinson's disease because these medications can affect dopamine levels in the brain. However, this condition is usually temporary.

The key differences are:

- Drug-induced parkinsonism doesn't cause actual Parkinson's disease
- Symptoms typically fade within weeks to a year after stopping the medication
- It's the second most common cause of parkinsonism symptoms after Parkinson's disease itself
- Unlike Parkinson's disease, drug-induced parkinsonism usually isn't progressive

Not everyone who takes these antidepressants will develop these symptoms. If you're experiencing parkinsonian symptoms while taking antidepressants, talk with your doctor about your medication options.

April 21

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