It's not a bad idea to get tests every few years for B6 and B12. After 6 years on c/l my husband was fine for B6 but somewhat low on B12 so we started a supplement.
July 3
Great question! Vyalev (foscarbidopa/foslevodopa) is a carbidopa/levodopa-based treatment, so yes, the same vitamin B6 deficiency risk applies.
The FDA's warning covers all medications containing carbidopa/levodopa, including those delivered via infusion. In fact, research suggests that people using carbidopa/levodopa Show Full Answer
Great question! Vyalev (foscarbidopa/foslevodopa) is a carbidopa/levodopa-based treatment, so yes, the same vitamin B6 deficiency risk applies.
The FDA's warning covers all medications containing carbidopa/levodopa, including those delivered via infusion. In fact, research suggests that people using carbidopa/levodopa intestinal gel (a similar delivery method) had an even higher rate of low B6 levels — nearly 45% — compared to about 30% for those taking oral carbidopa/levodopa. Here's what to watch for regarding low vitamin B6 levels:
- Numbness, tingling, or nerve pain
- Muscle weakness
- Depression or confusion
- Fatigue
- Skin or mouth inflammation
- In severe cases, seizures
It's a good idea to ask your doctor to check your B6 levels regularly, especially since infusion-based delivery tends to involve higher or continuous doses. Don't adjust your pump settings or stop treatment on your own — always loop in your care team first.
July 3
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