Four changes in my wife's medication made a huge difference in the hallucinations and delusions that my wife was suffering from. #1: taking quetiapine (Seroquel), as Jelsesr pointed out. This was probably the single most effective change--especially for the delusions. #2: eliminating amantadine. This also significantly reduced the hallucinations. #3: eliminating tramadol, which she was taking for pain. This removed the last of the consistent hallucination issues. #4: taking memantine. I think this has also helped to keep her more grounded. Hallucinations do pop up occasionally (not often), but she is able to see/accept that they are hallucinations, and they are not disturbing, which they had become before these medication changes. I sincerely hope that you spouse can get relief from the delusions. They were the most difficult part of the Parkinson's experience, so far, for both of us.

quetiapine. (Seroquel) is helping and I am also sleeping better

My husband has been taking a new medication Nuplazid at night to control for paranoia and hallucinations. Seroquel also low dose of about 75 mg.

Yes

Thank you, CharBw. .I hope I can convince the folks here to let me try Seroquel.