MyParkinsonsTeam

It sounds like your husband is going through a really difficult time, and it's completely understandable to be searching for answers. The symptoms you're describing — numbness, tingling, motion sickness, and significant weight loss — are worth taking seriously, and it's good that his medical team is continuing to Show Full Answer

It sounds like your husband is going through a really difficult time, and it's completely understandable to be searching for answers. The symptoms you're describing — numbness, tingling, motion sickness, and significant weight loss — are worth taking seriously, and it's good that his medical team is continuing to investigate.

Regarding Drug-Induced Parkinsonism (DIP), some of the medications your husband takes are known to interfere with dopamine activity in the brain. Medications like Rexulti and Seroquel belong to a class that can potentially trigger DIP symptoms.

Common DIP symptoms include:

- Tremors at rest
- Muscle stiffness
- Slowness of movement
- Balance and walking difficulties

DIP symptoms typically affect both sides of the body, unlike Parkinson's which usually starts on one side. The numbness, tingling, and motion sickness aren't classic DIP symptoms, which is likely why his doctors are continuing to investigate with further imaging. That's the right approach.

It's really important not to stop or change any medications without his doctor's guidance, even if DIP is suspected. A neurologist can order a DaTscan to help distinguish between DIP and Parkinson's disease if needed.

Other MyParkinsonsTeam members have navigated complex medication situations like this — sharing experiences there may offer some comfort while waiting for answers.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

Drug-Induced Parkinsonism: Causes, Symptoms, and Treatment