I’ve been on mirapex ER 1.5mg for 6 months. It was controlling my symptoms well but the last few weeks I seem to have more stiffness , pain, muscle spasms and worsening of tremors. Mirapex has caused me to have weight gain and some feet swelling so I’m also nervous that will get worse with dose increase . What dose are everyone else on?

My Neurologist has switched me from LevoDopa to Mirapex. He hopes this will solve my sever pain in my neck, shoulders, wrists and legs.

Take care everyone.

Weight gain friend up 60 lb. on mirapex Got off and lost it. I gained 30 and can’t lose any continue to gain Rytary and azilect and tasigline hate to change but getting all new clothes is not optiom

I’ve had DBS, but tremors have returned and I’m taking 8 Sinimet 25-100 daily. Started taking Mirapex (Pramipexole) again. It works pretty good but it’s interfering with my sleep again (4 hours per night with Mirapex vs 8-9 hours without it last week). Amantadine didn’t work at all previously, and I won’t keep taking Mirapex if it’s this disruptive. I’m starting accupuncture, but does anyone have any suggestions for agonists so I can discuss them with my neurologist?

My husband's neurologist just prescribed the Inbrijia inhaler to help with "off" times. He was taking the Apokyn injection as needed but it caused orthostatic hypotension (low blood pressure) and it he passed out (Apoykyn is not like levodopa but similar to Miralax). Inbrijia is a levodopa powder that goes into a rescue inhaler for those bad "off" times. He hasn't started it yet but was wondering if anyone has had experience with this new medication. Thanks.

I’m looking at alternative to sinemet